Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898792 | 0.89 | KIF11 (0.48) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4044366 | 0.83 | MEN1 (0.45) | ALDH1A1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL4891667 | 0.83 | HDAC2 (0.47) | ALDH1A1HTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL25037265 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30965893 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL940712 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL25037396 | 0.82 | ACHE (0.57) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL31082029 | 0.82 | KIF11 (0.51) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL25334235 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22897720 | 0.79 | TMPRSS4 (0.54) | ALDH1A1HTTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000067-B1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-10-23 | — | — | EP | disclosed |
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |
| EP-1000067-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005147-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1999-02-04 | — | — | WO | disclosed |