Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 8/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898792 | 0.93 | KIF11 (0.48) | HDAC2KIF11HDAC1ALDH1A1CYP1A2 | |
| SCHEMBL7388602 | 0.83 | ALDH1A1 (0.47) | HDAC1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3901609 | 0.81 | KIF11 (0.50) | HDAC2KIF11 | |
| SCHEMBL4608553 | 0.78 | KIF11 (0.57) | HDAC2KIF11ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4891673 | 0.77 | HDAC2 (0.43) | HDAC2KIF11HDAC1HDAC3AAK1 | |
| SCHEMBL4659870 | 0.72 | KIF11 (0.56) | KIF11 | |
| SCHEMBL5521041 | 0.72 | KIF11 (0.71) | KIF11 | |
| SCHEMBL25334235 | 0.70 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1261721 | 0.69 | ALDH1A1 (0.46) | KIF11ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL25037265 | 0.69 | ALDH1A1 (0.67) | HDAC1ALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | HDAC2 1216/4885KIF11 562/4885HDAC1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.