Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 14/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382928 | 0.93 | GAA (0.48) | KMT2ANAMPTPOLBNLRP3 | |
| SCHEMBL9394451 | 0.92 | KMT2A (0.48) | KMT2ANAMPTPOLBNLRP3 | |
| SCHEMBL9394066 | 0.88 | OPRK1 (0.40) | KMT2APOLBNLRP3 | |
| SCHEMBL7380058 | 0.84 | CTSG (0.40) | KMT2ANLRP3 | |
| SCHEMBL9394724 | 0.83 | KMT2A (0.39) | KMT2APOLBNLRP3 | |
| SCHEMBL7386038 | 0.82 | TSHR (0.42) | NAMPTPOLBNLRP3 | |
| SCHEMBL6978278 | 0.80 | KMT2A (0.47) | KMT2ANAMPTPOLB | |
| SCHEMBL7386075 | 0.79 | ALDH1A1 (0.43) | KMT2APOLB | |
| SCHEMBL9389734 | 0.79 | KMT2A (0.45) | KMT2ANAMPTPOLB | |
| SCHEMBL7962534 | 0.78 | KMT2A (0.44) | KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5475025-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| US-5314902-A | Thioureas and guanidine compounds, anticoagulants | MONSANTO COMPANY (US) | 1994-05-24 | — | — | US | disclosed |