Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976046 | 0.86 | POLB (0.46) | HTTFPR2PSMB11PSMA7PSMB1 | |
| SCHEMBL9394451 | 0.79 | KMT2A (0.48) | KMT2ANAMPT | |
| SCHEMBL9394054 | 0.78 | FAAH (0.41) | HTTMAPTFPR2PSMB11PSMA7 | |
| SCHEMBL9394724 | 0.78 | KMT2A (0.39) | KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL7389409 | 0.78 | KMT2A (0.47) | KMT2ANAMPT | |
| SCHEMBL7972470 | 0.77 | ITGB3 (0.53) | KDM4E | |
| SCHEMBL7382928 | 0.76 | GAA (0.48) | KMT2AHTTMAPTNAMPTALDH1A1 | |
| SCHEMBL7380058 | 0.73 | CTSG (0.40) | KMT2AALDH1A1 | |
| SCHEMBL9260575 | 0.73 | ITGA4 (0.43) | FPR2NAMPTCYP2C9 | |
| SCHEMBL9394066 | 0.73 | OPRK1 (0.40) | KMT2ATDP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | claimed |
| WO-1994019341-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-01 | — | — | WO | claimed |
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | disclosed |
| WO-1994019341-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-01 | — | — | WO | disclosed |