Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 13/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389409 | 0.92 | KMT2A (0.47) | KMT2APOLBNAMPTNLRP3 | |
| SCHEMBL7382928 | 0.85 | GAA (0.48) | KMT2APOLBNAMPTNLRP3 | |
| SCHEMBL9394724 | 0.84 | KMT2A (0.39) | KMT2APOLBNLRP3 | |
| SCHEMBL9394066 | 0.82 | OPRK1 (0.40) | KMT2APOLBNLRP3 | |
| SCHEMBL7380058 | 0.81 | CTSG (0.40) | KMT2ANLRP3 | |
| SCHEMBL7386038 | 0.80 | TSHR (0.42) | POLBNAMPTNLRP3 | |
| SCHEMBL7962534 | 0.79 | KMT2A (0.44) | KMT2ANAMPT | |
| SCHEMBL7976046 | 0.78 | POLB (0.46) | POLBNAMPT | |
| SCHEMBL6949829 | 0.78 | FAAH (0.41) | KMT2APOLBNLRP3 | |
| SCHEMBL7835677 | 0.77 | GPR132 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |