Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388174 | 0.89 | SIGMAR1 (0.42) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL27517334 | 0.87 | KMT2A (0.47) | LIPESIGMAR1ITGB3ITGA2BPRSS1 | |
| SCHEMBL7389816 | 0.86 | ITGB3 (0.45) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7387646 | 0.86 | SIGMAR1 (0.51) | LIPESIGMAR1ITGB3ITGA2BPRSS1 | |
| SCHEMBL7390332 | 0.84 | ITGB3 (0.46) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7381694 | 0.82 | KDM4E (0.44) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL27541054 | 0.81 | F10 (0.44) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7390212 | 0.81 | P2RX3 (0.43) | LIPESIGMAR1CHRM1KDM2B | |
| SCHEMBL7422648 | 0.81 | ITGB3 (0.42) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7384096 | 0.81 | ITGB3 (0.47) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1281451-A | Benzamidine derivatives | MERCK PATENT GMBH (DE) | 2001-01-24 | — | — | CN | disclosed |
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |