Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387537 | 0.88 | NLRP3 (0.54) | NLRP3KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL1549923 | 0.81 | NLRP3 (0.48) | NLRP3KDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL7391713 | 0.79 | NLRP3 (0.41) | NLRP3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4853553 | 0.79 | NLRP3 (0.45) | NLRP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11284651 | 0.76 | KDM4E (0.43) | NLRP3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7394140 | 0.74 | NLRP3 (0.57) | NLRP3KDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL29485565 | 0.74 | ALDH1A1 (0.47) | NLRP3KDM4ESMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11362896 | 0.74 | HSD17B10 (0.48) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13858739 | 0.73 | ALDH1A1 (0.53) | NLRP3KDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL10751671 | 0.72 | MEN1 (0.48) | KDM4EMEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |