Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387537 | 0.89 | NLRP3 (0.54) | NLRP3ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL7394140 | 0.83 | NLRP3 (0.57) | NLRP3ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL29485565 | 0.83 | ALDH1A1 (0.47) | NLRP3ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL7390785 | 0.81 | NLRP3 (0.46) | NLRP3ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL1549815 | 0.80 | ESR1 (0.54) | ALDH1A1CYP1A2NPSR1KDM4EHSD17B10 | |
| SCHEMBL7386523 | 0.80 | ATM (0.47) | NLRP3ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL7028752 | 0.80 | ALDH1A1 (0.58) | NLRP3ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL4853186 | 0.80 | ALDH1A1 (0.45) | NLRP3ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL4853553 | 0.80 | NLRP3 (0.45) | NLRP3ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL8194998 | 0.79 | CD69 (0.46) | NLRP3ALDH1A1CYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314576-A1 | Phenyl derivatives as PPAR agonists | F.HOFFMANN-LA ROCHE AG (CH) | 2011-04-27 | — | — | EP | disclosed |
| US-7112599-B2 | Oxazole compounds for the treatment of neurodegenerative disorders | PFIZER INC. (US) | 2006-09-26 | — | — | US | disclosed |
| EP-1682508-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049573-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |