Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457886 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL1919495 | 0.85 | HPGDS (0.52) | PIN1BRD4HPGDSLTA4HADRA1A | |
| SCHEMBL20599370 | 0.78 | PIN1 (0.43) | NPC1RAB9ASMN1; SMN2HPGDPIN1 | |
| SCHEMBL28477141 | 0.78 | LTA4H (0.46) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL2801771 | 0.78 | HPGDS (0.42) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL28594488 | 0.77 | GRM5 (0.47) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11363800 | 0.77 | BRD4 (0.57) | NPC1SMN1; SMN2TP53HPGDPIN1 | |
| SCHEMBL26259967 | 0.77 | BRD4 (0.53) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL3980022 | 0.76 | NOTUM (0.52) | NPC1RAB9ASMN1; SMN2NOTUMPIN1 | |
| SCHEMBL2264738 | 0.76 | BRD4 (0.45) | PIN1BRD4HPGDSLTA4HADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104649997-B | 2,4-dimethylthiazole acrylonitrile compound and application thereof | 沈阳中化农药化工研发有限公司 | 2017-05-10 | — | — | CN | disclosed |
| US-8137896-B2 | Method of preparing lithographic printing plates | EASTMAN KODAK COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| US-7294680-B2 | Method of producing conjugated diene polymers with narrow molecular weight distribution and polymer produced | JSR CORPORATION (JP) | 2007-11-13 | — | — | US | disclosed |
| EP-1026181-B1 | Method of producing conjugated diene polymer | JSR CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-20040147694-A1 | Method of producing conjugated diene polymers with narrow molecular weight distribution and polymer produced | JSR CORPORATION | 2004-07-29 | — | — | US | disclosed |
| EP-0957115-B1 | Method for producing conjugated diene polymers | JSR CORP (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-0863165-B1 | Method of producing conjugated diene polymers | JSR CORP (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6391990-B1 | Method of producing conjugated diene polymer | JSR CORPORATION (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6255416-B1 | POLYMERIZING CONJUGATED DIENE COMPOUND WITH CATALYST CONSISTING ESSENTIALLY OF COMPOUND CONTAINING RARE EARTH ELEMENT, ALUMOXANE, ORGANOALUMINUM COMPOUND, REACTION PRODUCT OF METAL HALIDE AND LEWIS BASE | JSR CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-1026181-A1 | Method of producing conjugated diene polymer | JSR Corporation (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0957115-A1 | Method for producing conjugated diene polymers | JSR Corporation (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0863165-A1 | Method of producing conjugated diene polymers | JSR Corporation (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-4758568-A | Quinoline therapeutic agents | PFIZER INC. (US) | 1988-07-19 | — | — | US | disclosed |
| CN-87105481-A | Mycocide and its production and use | — | 1988-03-30 | — | — | CN | disclosed |
| US-4686228-A | Quinoline therapeutic agents | PFIZER INC. (US) | 1987-08-11 | — | — | US | disclosed |
| EP-0219300-A2 | Electrophotographic plate | Hitachi Chemical Co., Ltd. (JP) | 1987-04-22 | — | — | EP | disclosed |
| EP-0218422-A2 | Semiconductor light-emitting element | KABUSHIKI KAISHA TOSHIBA (JP) | 1987-04-15 | — | — | EP | disclosed |
| US-4656174-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1987-04-07 | — | — | US | disclosed |