Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919495 | 0.85 | HPGDS (0.52) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL1855756 | 0.81 | ADRA1A (0.47) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL11363800 | 0.77 | BRD4 (0.57) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL26259967 | 0.77 | BRD4 (0.53) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL3980022 | 0.76 | NOTUM (0.52) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL9510279 | 0.76 | HPGDS (0.58) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL4904620 | 0.76 | ALDH1A1 (0.46) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL243773 | 0.76 | CASP3 (0.47) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL30457886 | 0.76 | NPC1 (0.53) | BRD4HPGDSLTA4HADRA1AADRA1D | |
| SCHEMBL4739891 | 0.76 | BRD4 (0.45) | BRD4HPGDSLTA4HADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748304-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM-FORMULATIONS AND USES | Marrone Bio Innovations, Inc. (US) | 2014-07-02 | — | — | EP | claimed |
| WO-2014088697-A2 | PLANT GLUTAMINE SYNTHETASE INHIBITORS AND METHODS FOR THEIR IDENTIFICATION | MARRONE BIO INNOVATIONS, INC. (US) | 2014-06-12 | — | — | WO | claimed |
| US-20140113816-A1 | PLANT GLUTAMINE SYNTHETASE INHIBITORS AND METHODS FOR THEIR IDENTIFICATION | PRO FARM GROUP, INC. | 2014-04-24 | — | — | US | claimed |
| CN-103261398-A | Isolated bacterial strains of the genus burkholderia and pesticide metabolites thereof | MARRONE BIO INNOVATIONS INC | 2013-08-21 | — | — | CN | claimed |
| WO-2013032693-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM-FORMULATIONS AND USES | MARRONE BIO INNOVATIONS, INC. (US) | 2013-03-07 | — | — | WO | claimed |
| EP-2539432-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | Marrone Bio Innovations, Inc. (US) | 2013-01-02 | — | — | EP | claimed |
| WO-2011106491-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | MARRONE BIO INNOVATIONS, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| US-20110207604-A1 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | MARRONE BIO INNOVATIONS (US) | 2011-08-25 | — | — | US | claimed |
| US-11793201-B2 | Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom | PRO FARM GROUP, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11382331-B2 | Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom | MARRONE BIO INNOVATIONS, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20200288715-A1 | Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom | MARRONE BIO INNOVATIONS, INC. (US) | 2020-09-17 | — | — | US | disclosed |
| US-20190313645-A1 | Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom | MARRONE BIO INNOVATIONS, INC. (US) | 2019-10-17 | — | — | US | disclosed |
| US-10159250-B2 | Isolated bacterial strain of the genus burkholderia and pesticidal metabolites therefrom | MARRONE BIO INNOVATIONS, INC. (US) | 2018-12-25 | — | — | US | disclosed |
| US-20180168166-A1 | Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom | PRO FARM GROUP, INC. | 2018-06-21 | — | — | US | disclosed |
| US-20140073501-A1 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | PRO FARM GROUP, INC. | 2014-03-13 | — | — | US | disclosed |
| CN-103261398-A | Isolated bacterial strains of the genus burkholderia and pesticide metabolites thereof | MARRONE BIO INNOVATIONS INC | 2013-08-21 | — | — | CN | disclosed |
| WO-2013032693-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM-FORMULATIONS AND USES | MARRONE BIO INNOVATIONS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| EP-2539432-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | Marrone Bio Innovations, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106491-A2 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | MARRONE BIO INNOVATIONS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20110207604-A1 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | MARRONE BIO INNOVATIONS (US) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382331-B2 | Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-20140073501-A1 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-20200288715-A1 | Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-20190313645-A1 | Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-20110207604-A1 | ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-20180168166-A1 | Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-20140113816-A1 | PLANT GLUTAMINE SYNTHETASE INHIBITORS AND METHODS FOR THEIR IDENTIFICATION | GLUL, ASNS, GLS | BRD4 1056/4885HPGDS 324/4885LTA4H 1503/4885 |
| US-11793201-B2 | Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
| US-10159250-B2 | Isolated bacterial strain of the genus burkholderia and pesticidal metabolites therefrom | NOTUM, WASF2, WEE1 | BRD4 600/4885HPGDS 1220/4885LTA4H 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.