Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | CPA1 | P15085 | 6/20 | 0.47 |
| ▸ | CPA3 | P15088 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14405551 | 0.83 | SLC15A1 (0.42) | ABCB1SLC15A1ALDH1A1ACE2ITGB3 | |
| SCHEMBL13687217 | 0.82 | ALDH1A1 (0.51) | ABCB1ALDH1A1MAPTHPGD | |
| SCHEMBL23699429 | 0.82 | CYP1A2 (0.51) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL2968658 | 0.79 | ITGB3 (0.59) | ABCB1FOLH1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL31739224 | 0.79 | ITGB3 (0.59) | ABCB1FOLH1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL2494968 | 0.79 | ITGB3 (0.59) | ABCB1FOLH1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL8067076 | 0.79 | ITGB3 (0.59) | ABCB1FOLH1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL358090 | 0.79 | ALDH1A1 (0.49) | ABCB1ALDH1A1MAPTHPGD | |
| SCHEMBL19541343 | 0.79 | ALDH1A1 (0.49) | CYP1A2ABCB1SLC15A1ALDH1A1SLC1A3 | |
| SCHEMBL26654515 | 0.78 | ITGB3 (0.58) | ABCB1FOLH1ALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670310-B1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5488037-A | ARGININE ALDEHYDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0671390-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0670310-A1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5436229-A | Di- and tripeptides as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-07-25 | — | — | US | disclosed |