Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394484 | 0.90 | MAPT (0.44) | KMT2ARAB9AHSD17B10MAPTMEN1 | |
| SCHEMBL7392654 | 0.90 | MEN1 (0.42) | KMT2ARAB9AMAPTMEN1NPC1 | |
| SCHEMBL7388874 | 0.82 | MAPT (0.44) | KMT2ARAB9AHSD17B10MAPTMEN1 | |
| SCHEMBL7210792 | 0.76 | MMP1 (0.43) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL7397231 | 0.76 | NPC1 (0.53) | ALDH1A1KMT2ARAB9AGAAHSD17B10 | |
| SCHEMBL7493288 | 0.74 | RAB9A (0.51) | ALDH1A1KMT2ARAB9AGAAHSD17B10 | |
| SCHEMBL7210495 | 0.72 | MMP2 (0.45) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL7210389 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KMT2ARAB9AHSD17B10MAPT | |
| SCHEMBL7393387 | 0.70 | MAPT (0.42) | ALDH1A1KMT2ARAB9AGAAMAPT | |
| SCHEMBL7210567 | 0.69 | MMP2 (0.55) | MMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | claimed |
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |