Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862074 | 0.78 | NPC1 (0.55) | ALDH1A1HPGDCYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL7439040 | 0.73 | L3MBTL1 (0.49) | HSP90AA1ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL9268650 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP1A2LMNARAB9A | |
| SCHEMBL18965005 | 0.69 | HTR3A (0.48) | HSP90AA1ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL7395463 | 0.68 | POLB (0.44) | ALDH1A1CYP1A2CYP2C19CYP2C9RAB9A | |
| SCHEMBL5769318 | 0.66 | HSP90AA1 (0.63) | HSP90AA1ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL9091364 | 0.66 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL29594813 | 0.65 | HTR3A (0.69) | HSP90AA1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3534699 | 0.65 | HTR3A (0.69) | HSP90AA1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8570130 | 0.64 | HSP90AA1 (0.47) | HSP90AA1ALDH1A1HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092257-A1 | OXO-IMIDAZOPYRIMIDINE-CARBOXAMIDES AND THEIR USE AS GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2001-12-06 | — | — | WO | claimed |