Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740573 | 0.79 | MAPK1 (0.58) | L3MBTL1ATMHTTLMNAGAA | |
| SCHEMBL7395401 | 0.74 | L3MBTL1 (0.51) | STING1L3MBTL1ATM | |
| SCHEMBL13518417 | 0.72 | MAOA (0.50) | STING1L3MBTL1MAOAPDE3BPDE3A | |
| SCHEMBL1609773 | 0.71 | STING1 (0.65) | STING1L3MBTL1MAOAPDE3BPDE3A | |
| SCHEMBL5224932 | 0.71 | STING1 (0.69) | STING1L3MBTL1MAOAHTTLMNA | |
| SCHEMBL11151272 | 0.70 | RXFP1 (0.68) | STING1L3MBTL1MAOAHTTLMNA | |
| SCHEMBL1609028 | 0.70 | STING1 (0.63) | STING1L3MBTL1ATMHTTLMNA | |
| SCHEMBL3747084 | 0.70 | NPC1 (0.38) | L3MBTL1ATMHTTLMNAGAA | |
| SCHEMBL3738095 | 0.69 | BCKDK (0.55) | HTTLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL10855114 | 0.69 | ASIC3 (0.40) | HTTLMNAGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955299-B1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-13 | — | — | EP | disclosed |
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |
| EP-0955299-A1 | Benzothiophene, benzofurane and indole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-11-10 | — | — | EP | disclosed |