Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929835 | 0.86 | HSD17B10 (0.46) | MAPTHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL12953530 | 0.81 | CYP1A2 (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29699525 | 0.79 | KMO (0.51) | MAPTLMNAACLYKIF11 | |
| SCHEMBL27699671 | 0.79 | ACLY (0.41) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL13581015 | 0.77 | KIF11 (0.41) | MAPTKDM4EGAAKIF11AURKA | |
| SCHEMBL16098500 | 0.77 | IGF2BP2 (0.52) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL16098765 | 0.77 | PTPN1 (0.50) | MAPTMEN1KMT2APTPN1IGF2BP2 | |
| SCHEMBL13581244 | 0.76 | FFAR4 (0.44) | KIF11HDAC2 | |
| SCHEMBL330530 | 0.76 | ALDH1A1 (0.55) | MAPTHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL6572975 | 0.75 | ALOX5 (0.52) | MAPTHSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |