Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398177 | 1.00 | LMNA (0.45) | LMNAEPHX2MMECHRNA1CHRNG | |
| SCHEMBL7399452 | 0.91 | TSHR (0.50) | NPY1RNPY4RKMT2A | |
| SCHEMBL7321414 | 0.85 | EPHX2 (0.54) | EPHX2NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7402598 | 0.84 | MMP1 (0.52) | EPHX2KMT2A | |
| SCHEMBL30291915 | 0.82 | NPY4R (0.54) | MMENPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30798296 | 0.82 | NPY4R (0.54) | MMENPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7440667 | 0.80 | NPY4R (0.58) | EPHX2FOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL29533534 | 0.80 | NPY4R (0.54) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29628189 | 0.78 | NPY4R (0.54) | MMENPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7416760 | 0.78 | ITGB3 (0.56) | LMNAFOLH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | claimed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | claimed |
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | disclosed |