Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397648 | 0.91 | LMNA (0.45) | NPY4RNPY1RKMT2A | |
| SCHEMBL7398177 | 0.91 | LMNA (0.45) | NPY4RNPY1RKMT2A | |
| SCHEMBL9058172 | 0.77 | NPY4R (0.56) | TSHRPOLBNPY4RNPY1RALDH1A1 | |
| SCHEMBL11125814 | 0.76 | ALDH1A1 (0.61) | TSHRPOLBATMALDH1A1THRB | |
| SCHEMBL7321414 | 0.76 | EPHX2 (0.54) | NPY4RNPY1R | |
| SCHEMBL7402598 | 0.76 | MMP1 (0.52) | KMT2A | |
| SCHEMBL31236264 | 0.75 | BIRC2 (0.60) | TSHRPOLBALDH1A1THRBCYP2C9 | |
| Aspartame SCHEMBL2099793 | 0.75 | NPY4R (0.57) | TSHRPOLBNPY4RNPY1RALDH1A1 | |
| Aspartame SCHEMBL2099790 | 0.75 | NPY4R (0.57) | TSHRPOLBNPY4RNPY1RALDH1A1 | |
| SCHEMBL10754676 | 0.74 | BIRC2 (0.61) | TSHRPOLBATMALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | claimed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | claimed |
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | disclosed |