Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398095 | 0.91 | KDM4E (0.38) | KDM4EPOLBNOS3NOS2MEN1 | |
| SCHEMBL7400302 | 0.85 | CXCR4 (0.34) | NOS3NOS2ALDH1A1LMNA | |
| SCHEMBL7594405 | 0.82 | NOS2 (0.44) | NOS3NOS2 | |
| SCHEMBL7424032 | 0.79 | NOS2 (0.45) | NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7398282 | 0.77 | NOS3 (0.43) | NOS3NOS2 | |
| SCHEMBL7401053 | 0.73 | ALDH1A1 (0.36) | NOS3NOS2KMT2AALDH1A1 | |
| SCHEMBL7423582 | 0.73 | NOS2 (0.41) | NOS3NOS2 | |
| SCHEMBL7397393 | 0.72 | NOS3 (0.37) | NOS3NOS2ALDH1A1 | |
| SCHEMBL7390644 | 0.70 | NOS3 (0.36) | POLBNOS3NOS2ALDH1A1 | |
| SCHEMBL7594951 | 0.70 | NOS3 (0.39) | NOS3NOS2MEN1KMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073312-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-07 | — | — | WO | claimed |