Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133802 | 0.88 | ALDH1A1 (0.44) | PTGS2ALDH1A1AKR1C3AKR1C2KMT2A | |
| SCHEMBL13074291 | 0.75 | ALDH1A1 (0.61) | ESR1AHRALDH1A1CALM1ABL1 | |
| SCHEMBL13485083 | 0.75 | ALDH1A1 (0.61) | ESR1AHRALDH1A1CALM1ABL1 | |
| SCHEMBL16957380 | 0.75 | ESR1 (0.45) | ESR1AHRPTGS2ALDH1A1CALM1 | |
| SCHEMBL7749051 | 0.72 | AOC3 (0.45) | POLB | |
| SCHEMBL8716433 | 0.71 | RAB9A (0.46) | PTGS2ALDH1A1AKR1C3AKR1C2ACACB | |
| SCHEMBL12180749 | 0.69 | PTGS2 (0.46) | ESR1AHRPTGS2ALDH1A1AKR1C3 | |
| SCHEMBL16959318 | 0.69 | ESR1 (0.46) | ESR1AHRPTGS2ALDH1A1CALM1 | |
| SCHEMBL14461578 | 0.68 | ESR1 (0.52) | ESR1AHRALDH1A1CALM1ABL1 | |
| SCHEMBL4617166 | 0.68 | CYP2D6 (0.37) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134986-B1 | BIOLOGICALLY ACTIVE HEPTAPEPTIDES, AGENTS THEREOF AND THEIR USE | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-12-27 | — | — | EP | claimed |
| US-4567162-A | ANIMAL GROWTH PROMOTERS | FARMITALIA CARLO ERBA (IT) | 1986-01-28 | — | — | US | claimed |
| EP-0134986-A2 | Biologically active heptapeptides, agents thereof and their use | FARMITALIA CARLO ERBA S.r.l. (IT) | 1985-03-27 | — | — | EP | claimed |
| US-4474765-A | Biologically active peptides | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-10-02 | — | — | US | claimed |
| EP-0002680-A2 | 4-Spectinomycylamin and its physiologically acceptable salts, method of preparation and pharmaceutical products containing these substances | Dr. Karl Thomae GmbH (DE) | 1979-07-11 | — | — | EP | claimed |
| EP-0428700-B1 | IRREVERSIBLE BOMBESIN ANTAGONISTS | ERBA CARLO SPA (IT) | 1994-05-04 | — | — | EP | disclosed |
| EP-0311392-B1 | Solution synthesis of an octapeptide | ERBA CARLO SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| EP-0380623-B1 | IRREVERSIBLE PEPTIDE LIGANDS FOR BOMBESIN RECEPTORS | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-09-29 | — | — | EP | disclosed |
| EP-0517913-A1 | INHIBITIONS OF ENDOTHELIN FORMATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992012170-A1 | INHIBITIONS OF ENDOTHELIN FORMATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-07-23 | — | — | WO | disclosed |
| EP-0175323-B1 | BIOLOGICALLY ACTIVE PEPTIDES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-04-29 | — | — | EP | disclosed |
| US-5100873-A | Bombesin antagonist, anticancer agents, oligopeptides | FARMITALIA CARLO ERBA (IT) | 1992-03-31 | — | — | US | disclosed |
| EP-0339193-A1 | Peptide ligands for bombesin receptors | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-11-02 | — | — | EP | disclosed |
| EP-0311391-A2 | New process for preparing an octapeptide | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-04-12 | — | — | EP | disclosed |
| US-4650788-A | Novel peptides having an immunostimulating action, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-17 | — | — | US | disclosed |
| EP-0183245-A2 | Animal growth promotant | FARMITALIA CARLO ERBA S.r.l. (IT) | 1986-06-04 | — | — | EP | disclosed |
| EP-0175323-A2 | Biologically active peptides, processes for preparing them and pharmaceutical compositions | FARMITALIA CARLO ERBA S.r.l. (IT) | 1986-03-26 | — | — | EP | disclosed |
| US-4567162-A | ANIMAL GROWTH PROMOTERS | FARMITALIA CARLO ERBA (IT) | 1986-01-28 | — | — | US | disclosed |
| EP-0134986-A2 | Biologically active heptapeptides, agents thereof and their use | FARMITALIA CARLO ERBA S.r.l. (IT) | 1985-03-27 | — | — | EP | disclosed |
| US-4474765-A | Biologically active peptides | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-10-02 | — | — | US | disclosed |