Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956788 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BMEN1KMT2AF10 | |
| SCHEMBL4940823 | 0.78 | KMT2A (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL171845 | 0.77 | MAPT (0.63) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9080516 | 0.76 | MEN1 (0.50) | MEN1KMT2AHRH3ALDH1A1GAA | |
| SCHEMBL15709155 | 0.76 | THRA (0.57) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8658603 | 0.76 | ITGB3 (0.40) | ITGB3ITGA2BMEN1KMT2AGFER | |
| SCHEMBL12082812 | 0.75 | LMNA (0.69) | ALDH1A1GAASMN1; SMN2LMNAMAPT | |
| SCHEMBL10422044 | 0.75 | MAPT (0.53) | ITGB3ITGA2BMEN1KMT2ADRD4 | |
| SCHEMBL7399688 | 0.75 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7958674 | 0.75 | MAPT (0.51) | MEN1KMT2AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |