Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.52 |
| ▸ | HTR3B | O95264 | 5/20 | 0.52 |
| ▸ | HTR3A | P46098 | 5/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21247013 | 0.98 | ADRB1 (0.50) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7863204 | 0.80 | CHKA (0.43) | TP53THRBHTTLMNAMAPT | |
| SCHEMBL4869797 | 0.78 | ALDH1A1 (0.43) | CYP1A2CYP3A4TP53THRBCYP2C19 | |
| SCHEMBL4138501 | 0.75 | ALDH1A1 (0.31) | CHRM2CHRM4CHRM1CHRM3CYP1A2 | |
| SCHEMBL3442203 | 0.75 | HTR7 (0.67) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5570604 | 0.74 | ADRB1 (0.77) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6350290 | 0.72 | CHRNB2 (0.51) | CYP1A2CYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL4915501 | 0.72 | HTR1A (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2548096 | 0.71 | HTR7 (0.51) | ADRB1SIGMAR1CYP1A2CYP3A4HTR1A | |
| SCHEMBL7082120 | 0.70 | ADRB1 (0.63) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775261-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115427404-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-115427404-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-107286174-B | Substituted 2,4- (1H,3H) pyrimidinedione as PARP inhibitor and application thereof | 上海勋和医药科技有限公司 | 2020-08-18 | — | — | CN | disclosed |
| EP-0971928-A1 | QUINOLINE-2(1H)-ONE AND DIHYDROQUINOLINE-2(1H)-ONE DERIVATIVES AS LIGANDS OF 5-HT, 5-HT2 AND 5-HT1-LIKE RECEPTORS | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042712-A1 | QUINOLINE-2(1H)-ONE AND DIHYDROQUINOLINE-2(1H)-ONE DERIVATIVES AS LIGANDS OF 5-HT, 5-HT2 AND 5-HT1-LIKE RECEPTORS | SANOFI-SYNTHELABO (FR) | 1998-10-01 | — | — | WO | disclosed |
| EP-0041891-A1 | 6-Methyl-4-(1-piperazinyl)-furo(3,2-c)pyridines, process for their preparation and their therapeutic use | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1981-12-16 | — | — | EP | disclosed |
| EP-0041891-A1 | 6-Methyl-4-(1-piperazinyl)-furo(3,2-c)pyridines, process for their preparation and their therapeutic use | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1981-12-16 | — | — | EP | disclosed |
| WO-1981003493-A1 | 4-(1-PIPERAZINYL)-FURO(3,2C)PYRIDINE DERIVATIVES,PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CERM CENT EUROP RECH MAUVERNAY (FR) | 1981-12-10 | — | — | WO | disclosed |