Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | GRN | P28799 | 2/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401270 | 1.00 | CA2 (0.55) | CA2CA1CASP3GRNSORT1 | |
| SCHEMBL7370211 | 0.84 | CA2 (0.51) | CA2CA1CASP3GRNSORT1 | |
| SCHEMBL7394132 | 0.83 | ROCK2 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL6434979 | 0.79 | CA2 (0.46) | CA2CA1CASP3TMPRSS15 | |
| Trifluoroacetic Acid SCHEMBL6434983 | 0.79 | CA2 (0.46) | CA2CA1CASP3TMPRSS15 | |
| SCHEMBL7403830 | 0.77 | PLAU (0.52) | CA2 | |
| SCHEMBL6437559 | 0.76 | ROCK2 (0.38) | CA2CA1GRNSORT1 | |
| SCHEMBL6433486 | 0.74 | PLAU (0.51) | — | |
| SCHEMBL6433807 | 0.74 | GRN (0.46) | CA2CA1GRNSORT1 | |
| SCHEMBL6434625 | 0.74 | NPSR1 (0.48) | CA2CA1GRNSORT1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |