Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486439 | 0.80 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7493829 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL7486656 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL8459092 | 0.78 | ITGAV (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399462 | 0.77 | ITGB3 (0.79) | ITGB3ITGA2BITGAV | |
| SCHEMBL8348648 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BITGAVMMP13KDM4E | |
| SCHEMBL16385073 | 0.77 | ITGB3 (0.59) | ITGB3ITGA2BITGAVMMP13GPR119 | |
| SCHEMBL8903718 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7490103 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7401949 | 0.76 | GPR119 (0.54) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |