Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17725584 | 0.81 | KMT2A (0.58) | KMT2AMAPTTP53NPC1RAB9A | |
| SCHEMBL1955285 | 0.77 | ABL1 (0.46) | KMT2AL3MBTL1MAPTTP53NPC1 | |
| SCHEMBL31227596 | 0.76 | RARA (0.47) | KMT2AL3MBTL1MAPTTP53NPC1 | |
| SCHEMBL1956751 | 0.76 | KDM4E (0.56) | KMT2AL3MBTL1MAPTTP53NPC1 | |
| SCHEMBL19767755 | 0.75 | SLC6A3 (0.69) | KMT2AL3MBTL1MAPTTP53RAB9A | |
| SCHEMBL12909247 | 0.75 | ACHE (0.46) | KMT2AMAPTTP53NPC1RAB9A | |
| SCHEMBL18031477 | 0.74 | MAPT (0.53) | KMT2AL3MBTL1MAPTTP53NPC1 | |
| SCHEMBL630337 | 0.73 | SLC6A3 (0.65) | KMT2AL3MBTL1MAPTHTTSLC6A3 | |
| SCHEMBL26493737 | 0.72 | SLC6A3 (0.52) | L3MBTL1MAPTTP53SLC6A3ABCG2 | |
| SCHEMBL7368865 | 0.72 | OPRK1 (0.39) | KMT2AMAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995027692-A1 | SUBTITUTED BIPHENYL TNF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-19 | — | — | WO | disclosed |