Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076478 | 0.91 | CPN1 (0.36) | CPN1CPB2ITGB3ITGA2BITGAV | |
| SCHEMBL14941825 | 0.83 | CPN1 (0.47) | CPN1CPB2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9386830 | 0.81 | ALDH1A1 (0.40) | CPN1CPB2SLC6A4ALDH1A1TSHR | |
| SCHEMBL6207747 | 0.78 | ITGB3 (0.34) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6058467 | 0.77 | TSHR (0.52) | ALDH1A1TSHRATMEPHX1 | |
| SCHEMBL30166189 | 0.77 | SLC6A3 (0.40) | SLC6A4ALDH1A1 | |
| SCHEMBL25429500 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL5724460 | 0.76 | ALDH1A1 (0.38) | SLC6A4ALDH1A1TSHRGNAI3GNAO1 | |
| SCHEMBL14942027 | 0.75 | SLC6A3 (0.45) | SLC6A4ALDH1A1TSHR | |
| SCHEMBL11395732 | 0.75 | L3MBTL1 (0.53) | CPN1CPB2SLC6A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |