Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122407 | 0.92 | MMP1 (0.40) | LMNASMN1; SMN2TSHRSLC6A2SLC6A4 | |
| SCHEMBL5724460 | 0.91 | ALDH1A1 (0.38) | ALDH1A1GNAI3GNAO1GNAI1ATM | |
| SCHEMBL7401485 | 0.81 | CPN1 (0.41) | ALDH1A1GNAI3GNAO1GNAI1ATM | |
| SCHEMBL25429500 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GNAI3GNAO1GNAI1ATM | |
| SCHEMBL1076478 | 0.76 | CPN1 (0.36) | ALDH1A1ATMCPN1CPB2TSHR | |
| SCHEMBL18307376 | 0.75 | SLC6A3 (0.46) | ALDH1A1EPHX1CPN1CPB2POLB | |
| SCHEMBL8569265 | 0.75 | PRCP (0.41) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6207732 | 0.75 | PRCP (0.41) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3982507 | 0.75 | PRCP (0.41) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4917731 | 0.75 | GNAI3 (0.47) | ALDH1A1GNAI3GNAO1GNAI1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604494-A1 | 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-06 | — | — | EP | disclosed |