Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824468 | 1.00 | GRM5 (0.53) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL15940575 | 0.94 | GRM5 (0.49) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| Thiophene SCHEMBL15940611 | 0.89 | GRM5 (0.45) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| Toluene SCHEMBL27946106 | 0.89 | CYP1A2 (0.47) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL15940691 | 0.83 | GRM5 (0.41) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL10788654 | 0.77 | GRM5 (0.53) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL29359679 | 0.77 | GRM5 (0.53) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL194312 | 0.77 | GRM5 (0.53) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL3059086 | 0.77 | GRM5 (0.53) | GRM5KCNH2NCF1CYP1A2NOS2 | |
| SCHEMBL75226 | 0.77 | GRM5 (0.53) | GRM5KCNH2NCF1CYP1A2NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083813-A | A kind of synthetic method of triazole quinolines | 太原理工大学 | 2016-11-09 | — | — | CN | claimed |
| CN-120442103-A | Preparation method of cold-resistant low-temperature printing ink | 哈尔滨金龙盛印刷材料有限公司 | 2025-08-08 | — | — | CN | disclosed |
| US-20250163088-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | DEBRECENI EGYETEM (HU) | 2025-05-22 | — | — | US | disclosed |
| CN-119912441-A | Novel oxazolidinone compound and anti-infection application thereof | 安徽医科大学第一附属医院 | 2025-05-02 | — | — | CN | disclosed |
| CN-119792542-A | Method for accelerating bio-orthogonal catalysis of acid/reduction sensitive polymer vesicles in situ of tumor | 苏州大学 | 2025-04-11 | — | — | CN | disclosed |
| WO-2025076285-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| EP-4463230-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | Debreceni Egyetem (HU) | 2024-11-20 | — | — | EP | disclosed |
| WO-2024051720-A1 | 5-PYRIDINE-1H-INDAZOLE COMPOUND FOR TARGETED INHIBITION OF CLK2 AND USE OF COMPOUND | 中国药科大学 | 2024-03-14 | — | — | WO | disclosed |
| CN-115304583-B | 5-pyridine-1H-indazole compound for targeted inhibition of CLK2 and application thereof | 中国药科大学 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023041947-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | DEBRECENI EGYETEM (HU) | 2023-03-23 | — | — | WO | disclosed |
| US-20050192212-A1 | Macrocyclic peptides active against the hepatitis C virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-09-01 | — | — | US | disclosed |
| WO-2005070955-A1 | MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-08-04 | — | — | WO | disclosed |
| US-20050165052-A1 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2005-07-28 | — | — | US | disclosed |
| CN-1200925-C | Aromatic carboxylic acid compound, acid halide derivative thereof, and process for producing the same | SUMITOMO BAKELITE CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| CN-1474800-A | Aromatic carboxylic acid compound, acid halide derivative thereof, and process for producing the same | 住友电木株式会社 | 2004-02-11 | — | — | CN | disclosed |
| EP-1351940-A1 | SUBSTITUTED QUINOLINES FOR THE TREATMENT OF PROTOZOAN AND RETROVIRUS CO-INFECTIONS | Institut de Recherche pour le Développement ( IRD) (FR) | 2003-10-15 | — | — | EP | disclosed |
| EP-1346975-A1 | AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH | SUMITOMO BAKELITE CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002057238-A1 | SUBSTITUTED QUINOLINES FOR THE TREATMENT OF PROTOZOAN AND RETROVIRUS CO-INFECTIONS | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD) (FR) | 2002-07-25 | — | — | WO | disclosed |
| WO-2002055077-A1 | USE OF IMIDAZOLYL CYCLIC ACETAL DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DISEASES MEDIATED BY THE ALK5 RECEPTORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192212-A1 | Macrocyclic peptides active against the hepatitis C virus | CTRL, RNPEP, RNASE1 | GRM5 4838/4885KCNH2 2609/4885NCF1 2188/4885 |
| US-20050165052-A1 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | C1S, C5, NSFL1C | GRM5 2484/4885KCNH2 259/4885NCF1 2296/4885 |
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | CCR1, CCRL2, CCR6 | GRM5 3878/4885KCNH2 2712/4885NCF1 1540/4885 |
| US-20250163088-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | SLC39A3, CUTA, SLC30A6 | GRM5 3296/4885KCNH2 4631/4885NCF1 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.