Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.48 |
| ▸ | CTSK | P43235 | 14/20 | 0.48 |
| ▸ | CTSL | P07711 | 14/20 | 0.48 |
| ▸ | CTSB | P07858 | 14/20 | 0.48 |
| ▸ | CTSV | O60911 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401952 | 0.85 | CTSS (0.51) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7405812 | 0.85 | CTSK (0.62) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7394745 | 0.84 | CTSL (0.59) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7399686 | 0.82 | CTSS (0.47) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7395140 | 0.82 | CTSS (0.44) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7447689 | 0.82 | CTSS (0.43) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7405777 | 0.81 | CTSL (0.45) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7400496 | 0.81 | CTSS (0.60) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7447450 | 0.80 | CTSK (0.54) | CTSSCTSKCTSLCTSBCTSV | |
| SCHEMBL7439946 | 0.79 | CTSK (0.51) | CTSSCTSKCTSLCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | disclosed |