Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.51 |
| ▸ | CTSL | P07711 | 11/20 | 0.51 |
| ▸ | CTSB | P07858 | 10/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSV | O60911 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399686 | 0.92 | CTSS (0.47) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7401735 | 0.85 | CTSS (0.48) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7400496 | 0.84 | CTSS (0.60) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7394745 | 0.83 | CTSL (0.59) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7395140 | 0.83 | CTSS (0.44) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7405812 | 0.82 | CTSK (0.62) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7400518 | 0.82 | CTSS (0.47) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7441160 | 0.82 | CTSS (0.43) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7405777 | 0.82 | CTSL (0.45) | CTSSCTSLCTSBCTSKCTSV | |
| SCHEMBL7396975 | 0.81 | CTSS (0.44) | CTSSCTSLCTSBCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | disclosed |