Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279211 | 0.87 | PTGS2 (0.51) | ALDH1A1CYP2C9CYP2C19PTGS2MAPT | |
| SCHEMBL11660766 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19PTGS2MAPT | |
| SCHEMBL1706669 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13846320 | 0.84 | L3MBTL1 (0.43) | CYP2C19MAPTL3MBTL1KMT2AGAA | |
| SCHEMBL2116437 | 0.81 | PTGS2 (0.66) | ALDH1A1CYP2C9CYP2C19PTGS2MAPT | |
| SCHEMBL23542808 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5743825 | 0.80 | PARP10 (0.58) | ALDH1A1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL10299626 | 0.80 | PTGS2 (0.57) | ALDH1A1CYP2C9CYP2C19PTGS2MAPT | |
| SCHEMBL4262664 | 0.78 | MAPT (0.70) | PTGS2MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL6960461 | 0.78 | L3MBTL1 (0.61) | ALDH1A1CYP2C9CYP2C19PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |