Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198621 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL7401820 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14198615 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL8382724 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL8382728 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL5743825 | 0.83 | PARP10 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8383676 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL10557960 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8383678 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL1705733 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572795-A2 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS | The University of Chicago (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20250114441-A1 | POLYMERIC VACCINE FOR OPIOID ADDICTION | THE JOHNS HOPKINS UNVERSITY | 2025-04-10 | — | — | US | disclosed |
| US-20240400684-A1 | ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-12-05 | — | — | US | disclosed |
| WO-2024040169-A2 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS | THE UNIVERSITY OF CHICAGO (US) | 2024-02-22 | — | — | WO | disclosed |
| US-11484599-B2 | Polymer conjugate vaccines | THE UNIVERSITY OF CHICAGO (US) | 2022-11-01 | — | — | US | disclosed |
| CN-108770357-B | Polymer conjugate vaccines | 芝加哥大学 | 2022-10-28 | — | — | CN | disclosed |
| US-20220305135-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-TARGETED ADJUVANTS | THE UNIVERSITY OF CHICAGO (US) | 2022-09-29 | — | — | US | disclosed |
| EP-3976061-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-TARGETED ADJUVANTS | The University of Chicago (US) | 2022-04-06 | — | — | EP | disclosed |
| CN-114206355-A | Methods and compositions for treating cancer with cancer-targeting adjuvants | 芝加哥大学 | 2022-03-18 | — | — | CN | disclosed |
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-11 | — | — | US | disclosed |
| WO-2005068458-A2 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF SRC FAMILY PROTEIN KINASE | SIRENADE PHARMACEUTICALS AG (DE) | 2005-07-28 | — | — | WO | disclosed |
| US-20050164296-A1 | reaction product of a meso-porous organofunctional silica and a ligand; organofunctional silica is prepared from an alkyl silicate and at least one organofunctional silane which contains a group reactive with ligand functional group | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2005-07-28 | — | — | US | disclosed |
| EP-1360004-B1 | CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2005-05-25 | — | — | EP | disclosed |
| EP-1360004-A1 | CATALYSTS | Johnson Matthey PLC (GB) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002066159-A1 | CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2002-08-29 | — | — | WO | disclosed |
| US-6127191-A | SOLID SUPPORT HAVING PLURALITY OF PENDANT SCAFFOLD MOIETIES COVALENTLY ATTACHED; FOR SYNTHESIS OF BIOACTIVE MOLECULES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1998024760-A1 | AMINOBENZENEDICARBOXYLIC ACID-BASED COMBINATORIAL LIBRARIES | GRAYBILL TODD L (US) | 1998-06-11 | — | — | WO | disclosed |
| EP-0708751-A1 | SYNTHESIS OF COMBINATORIAL ARRAYS OF ORGANIC COMPOUNDS THROUGH THE USE OF MULTIPLE COMPONENT COMBINATORIAL ARRAY SYNTHESES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002566-A1 | SYNTHESIS OF COMBINATORIAL ARRAYS OF ORGANIC COMPOUNDS THROUGH THE USE OF MULTIPLE COMPONENT COMBINATORIAL ARRAY SYNTHESES | ONTOGEN CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11484599-B2 | Polymer conjugate vaccines | CD14, TLR3, TLR1 | ALDH1A1 4596/4885TSHR 1379/4885ALOX15 2767/4885 |
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | CTSS, CTSK, CTSF | ALDH1A1 3777/4885TSHR 4214/4885ALOX15 1907/4885 |
| US-20220305135-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-TARGETED ADJUVANTS | TLR3, TLR6, TLR2 | ALDH1A1 4206/4885TSHR 2525/4885ALOX15 1380/4885 |
| US-20250114441-A1 | POLYMERIC VACCINE FOR OPIOID ADDICTION | OPRM1, OPRK1, OPRL1 | ALDH1A1 2483/4885TSHR 1132/4885ALOX15 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.