SCHEMBL6960461

SCHEMBL6960461

COC(=O)COc1ccc(C(C)=O)cc1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.61
GAA P10253 1/20 0.59
MAPT P10636 5/20 0.56
LMNA P02545 2/20 0.56
POLB P06746 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
PTGS2 P35354 2/20 0.55
HPGD P15428 1/20 0.53
RAB9A P51151 1/20 0.53
MAOB P27338 2/20 0.53
ALDH1A1 P00352 2/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL11664406 0.92 L3MBTL1 (0.53) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL2116437 0.88 PTGS2 (0.66) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL10299626 0.87 PTGS2 (0.57) L3MBTL1GAAMAPTLMNAPOLB
Urethane SCHEMBL11661385 0.87 POLB (0.49) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL10705419 0.86 PTGS2 (0.53) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL4262664 0.85 MAPT (0.70) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL3528003 0.85 PLA2G4B (0.62) MAPTPOLBPTGS2RAB9A
SCHEMBL10364396 0.85 PTGS2 (0.58) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL7327630 0.84 L3MBTL1 (0.51) L3MBTL1GAAMAPTLMNAPOLB
SCHEMBL8770195 0.84 POLB (0.70) L3MBTL1GAAMAPTPOLBPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025110772-A1 IMIDAZOLO-PYRIDINE DERIVATIVES AND USES THEREOF 엘젠테라퓨틱스 주식회사 2025-05-30 WO disclosed
US-20230200386-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS HERBICIDES IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-06-29 US disclosed
US-8759355-B2 Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) 2014-06-24 US disclosed
US-20110009427-A1 ARYL PYRIMIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF INSTITUE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) 2011-01-13 US disclosed
EP-2184277-A1 ARYL PYRIMIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) 2010-05-12 EP disclosed
EP-0729465-B1 PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE DAVIS & CO (US) 2003-01-22 EP disclosed
US-6005103-A TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS WARNER-LAMBERT COMPANY (US) 1999-12-21 US disclosed
US-5922717-A ANTICOAGULANTS DR. KARL THOMAE GMBH (DE) 1999-07-13 US disclosed
US-5700801-A ANTIINFLAMMATORY AGENTS, BONE DISORDERS KARL THOMAE, GMBH (DE) 1997-12-23 US disclosed
WO-1996020173-A1 PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME DR. KARL THOMAE GMBH (DE) 1996-07-04 WO disclosed
EP-0718287-A2 Piperazine derivatives, medicaments containing them, their use, and processes for their preparation Dr. Karl Thomae GmbH (DE) 1996-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200386-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS HERBICIDES DDT, CYP4B1, GSTO1 L3MBTL1 1489/4885GAA 1582/4885MAPT 3033/4885
US-20110009427-A1 ARYL PYRIMIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF PPARD, PPARG, PPARA L3MBTL1 4830/4885GAA 979/4885MAPT 4358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.