Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7965054 | 0.94 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAPTPRCMAPT | |
| SCHEMBL7400463 | 0.83 | FFAR4 (0.61) | ALDH1A1LMNAGAAPTPRCMAPT | |
| SCHEMBL7400836 | 0.81 | PTPRC (0.48) | ALDH1A1LMNAGAAPTPRCMAPT | |
| SCHEMBL14403378 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAGAAPTPRCMAPT | |
| Bromide SCHEMBL7981260 | 0.80 | PTPRC (0.47) | ALDH1A1LMNAGAAPTPRCMAPT | |
| SCHEMBL7401941 | 0.74 | LMNA (0.60) | ALDH1A1LMNAPTPRCMAPTMAPK1 | |
| SCHEMBL26028406 | 0.74 | TRPA1 (0.45) | LMNA | |
| SCHEMBL2005010 | 0.74 | CA12 (0.81) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL11976998 | 0.73 | ALDH1A1 (0.64) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL19364119 | 0.73 | GAA (0.64) | ALDH1A1LMNAGAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097921-A1 | Phenylhydrazines | SANOFI-SYNTHELABO (FR) | 2001-05-09 | — | — | EP | disclosed |
| EP-0820444-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996032382-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1996-10-17 | — | — | WO | disclosed |