Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | C1S | P09871 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401067 | 0.79 | PKM (0.37) | — | |
| SCHEMBL8539205 | 0.78 | — | — | |
| SCHEMBL7398815 | 0.72 | F10 (0.45) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7275049 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2BCPN1CPB2F2 | |
| SCHEMBL7272904 | 0.71 | TPH1 (0.50) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7283838 | 0.70 | PPARG (0.44) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7274415 | 0.70 | ITGB3 (0.42) | ITGB3ITGA2BCPN1CPB2F2 | |
| SCHEMBL7403166 | 0.69 | ITGB3 (0.45) | ITGB3ITGA2BCPN1CPB2F2 | |
| Hydrochloric Acid SCHEMBL7404704 | 0.69 | ALOX15 (0.44) | ITGB3ITGA2BCPN1CPB2F2 | |
| SCHEMBL7276107 | 0.68 | ITGB3 (0.67) | ITGB3ITGA2BF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |