Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 6/20 | 0.46 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8417536 | 0.99 | GPR88 (0.45) | GPR88LARS1ANPEPCTSBMEN1 | |
| SCHEMBL8645012 | 0.89 | AAK1 (0.43) | GPR88ANPEPCTSBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7400787 | 0.88 | AAK1 (0.42) | GPR88ANPEPCTSBMEN1KMT2A | |
| SCHEMBL8639130 | 0.84 | ANPEP (0.44) | GPR88ANPEPCTSBMEN1PLA2G1B | |
| Hydrochloric Acid SCHEMBL7398161 | 0.84 | NOS3 (0.41) | GPR88MEN1KMT2AAAK1LTA4H | |
| SCHEMBL2163674 | 0.82 | GPR88 (0.53) | GPR88LARS1ANPEPCTSBAAK1 | |
| SCHEMBL8640058 | 0.81 | CTSB (0.40) | GPR88ANPEPCTSBMEN1PLA2G1B | |
| SCHEMBL10533268 | 0.81 | KCNA5 (0.42) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL23923952 | 0.80 | KMT2A (0.42) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL421787 | 0.80 | KMT2A (0.42) | MEN1PLA2G1BHTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755405-A1 | PHOSPHONYLDIPEPTIDES USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES | ZAMBON GROUP S.p.A. (IT) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028417-A1 | PHOSPHONYLDIPEPTIDES USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISEASES | ZAMBON GROUP S.P.A. (IT) | 1995-10-26 | — | — | WO | disclosed |