Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | CTSL | P07711 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 9/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 7/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447450 | 0.79 | CTSK (0.54) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL7405812 | 0.78 | CTSK (0.62) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL4714857 | 0.77 | CTSK (0.62) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7404362 | 0.76 | CTSK (0.50) | CTSKCTSLCTSBCTSSPRKD1 | |
| SCHEMBL7401645 | 0.75 | CTSL (0.60) | CTSKCTSLKMT2ACTSBCTSS | |
| SCHEMBL7398927 | 0.74 | CTSK (0.63) | CTSKCTSLKMT2ACTSBCTSS | |
| SCHEMBL7392828 | 0.73 | CTSS (0.38) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL7399686 | 0.72 | CTSS (0.47) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL7401952 | 0.71 | CTSS (0.51) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL7439946 | 0.71 | CTSK (0.51) | CTSKCTSLCTSBCTSSCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | disclosed |