Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710319 | 0.87 | CA12 (0.46) | HTTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL9369968 | 0.85 | L3MBTL1 (0.52) | SMN1; SMN2CA12CA1CA9L3MBTL1 | |
| SCHEMBL11815908 | 0.84 | L3MBTL1 (0.58) | HTTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL11202364 | 0.78 | EPHX2 (0.50) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL8780766 | 0.78 | CA12 (0.56) | CA12CA1CA9L3MBTL1ALDH1A1 | |
| SCHEMBL29675123 | 0.78 | FDPS (0.66) | HTTSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL7866969 | 0.77 | ALDH1A1 (0.58) | HTTSMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11911915 | 0.75 | BIRC5 (0.47) | HTTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL241884 | 0.75 | CA1 (0.52) | HTTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL1640016 | 0.75 | CA12 (0.48) | HTTSMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503067-A | HYPOTENSIVE, ANGINA PECTORIS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-03-05 | — | — | US | disclosed |