Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 3/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402703 | 0.88 | HTR1A (0.35) | APOL1HTR1BHTR1DHTR1ASLC6A4 | |
| SCHEMBL7408320 | 0.86 | HTR1A (0.46) | APOL1HTR1BHTR1DHTR1ASLC6A4 | |
| SCHEMBL7410643 | 0.82 | DRD2 (0.44) | HTR1BHTR1DHTR1ADRD2DRD3 | |
| SCHEMBL7407950 | 0.82 | TMEM97 (0.39) | APOL1HTR1BHTR1DHTR1ASLC6A4 | |
| SCHEMBL7416195 | 0.81 | RB1 (0.41) | HTR1BHTR1DHTR1ASLC6A4DRD2 | |
| SCHEMBL7411050 | 0.81 | GRIN2B (0.47) | DRD2DRD3TMEM97 | |
| SCHEMBL7408004 | 0.81 | APOL1 (0.43) | APOL1HTR1BHTR1DHTR1ACFTR | |
| SCHEMBL7404555 | 0.80 | DRD2 (0.39) | HTR1BHTR1DDRD2DRD3 | |
| SCHEMBL11344966 | 0.80 | APOL1 (0.38) | APOL1HTR1BHTR1DHTR1ASLC6A4 | |
| SCHEMBL7408795 | 0.79 | VPS4B (0.36) | HTR1BHTR1DHTR1ASLC6A4TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |