Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 7/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19664384 | 0.79 | KMT2A (0.45) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4930416 | 0.78 | GABRG2 (0.49) | HCRTR2HCRTR1MGLLGRM5ACACB | |
| SCHEMBL15224439 | 0.77 | MGLL (0.47) | HCRTR2HCRTR1MGLLMEN1KMT2A | |
| SCHEMBL10672147 | 0.77 | RECQL (0.41) | ACACBKMT2A | |
| SCHEMBL3077434 | 0.77 | KDM4E (0.48) | HCRTR2HCRTR1GRM5PDCD1CD274 | |
| SCHEMBL10677536 | 0.74 | CYP4F2 (0.44) | ACACBKMT2A | |
| SCHEMBL7462116 | 0.74 | NUDT1 (0.35) | ACACBMEN1GAAKMT2A | |
| SCHEMBL27920318 | 0.73 | MGLL (0.42) | HCRTR2HCRTR1MGLLACACB | |
| SCHEMBL2770972 | 0.72 | CYP4F2 (0.42) | HCRTR2HCRTR1GRM5PDCD1CD274 | |
| SCHEMBL481549 | 0.72 | LMNA (0.49) | MEN1GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941226-A1 | (2,3-DIHYDROBENZOFURANYL)-THIAZOLES AS PHOSPHODIESTERASE INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998021207-A1 | (2,3-DIHYDROBENZOFURANYL)-THIAZOLES AS PHOSPHODIESTERASE INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-05-22 | — | — | WO | disclosed |