Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416511 | 0.89 | YAP1 (0.41) | ALDH1A1KDM4EYAP1HSD17B10 | |
| SCHEMBL7412325 | 0.88 | ALDH1A1 (0.33) | ALDH1A1KDM4EYAP1NPC1RAB9A | |
| SCHEMBL7408236 | 0.86 | LMNA (0.38) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL6777423 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7410744 | 0.81 | SERPINH1 (0.39) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7409675 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL6368737 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7405436 | 0.76 | NPC1 (0.34) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL7417466 | 0.73 | CA2 (0.39) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL7269670 | 0.73 | SERPINH1 (0.40) | ALDH1A1KDM4EMAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |