Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 4/20 | 0.31 |
| ▸ | CA7 | P43166 | 4/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.31 |
| ▸ | CA4 | P22748 | 3/20 | 0.31 |
| ▸ | CA3 | P07451 | 3/20 | 0.31 |
| ▸ | CA6 | P23280 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408236 | 0.87 | LMNA (0.38) | SMN1; SMN2ALDH1A1KDM4EMAPTPKM | |
| SCHEMBL7416511 | 0.85 | YAP1 (0.41) | CA2CA12CA1CA9HSD17B10 | |
| SCHEMBL7405436 | 0.84 | NPC1 (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL12598051 | 0.78 | ACLY (0.33) | SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7406591 | 0.78 | HSD17B10 (0.38) | CA2CA1SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11152798 | 0.75 | ALDH1A1 (0.42) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL7410107 | 0.73 | ALDH1A1 (0.35) | SMN1; SMN2HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL7412325 | 0.72 | ALDH1A1 (0.33) | ALDH1A1KDM4EPKM | |
| SCHEMBL1548498 | 0.72 | ALOX5 (0.38) | SMN1; SMN2HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL7413113 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |