Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 3/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411523 | 0.95 | OXER1 (0.44) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7410219 | 0.92 | LMNA (0.49) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7412570 | 0.87 | LMNA (0.48) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7407743 | 0.86 | NR4A2 (0.44) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7410285 | 0.86 | GAA (0.50) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8621598 | 0.85 | LMNA (0.47) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7469182 | 0.81 | LMNA (0.47) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7414744 | 0.81 | PBRM1 (0.44) | KDM4EMAPTHTTPIM1ALOX5 | |
| SCHEMBL7416125 | 0.78 | NPC1 (0.39) | LMNAMAPTHTTALOX5NR4A2 | |
| SCHEMBL31212857 | 0.74 | PPARA (0.50) | LMNAALDH1A1HTTHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5212195-A | Substituted indole antagonists derivatives which are angiotensin II | SYNTEX (U.S.A.) INC. (US) | 1993-05-18 | — | — | US | disclosed |