Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410219 | 0.92 | LMNA (0.49) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL7469182 | 0.86 | LMNA (0.47) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL7410235 | 0.85 | LMNA (0.44) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL7411523 | 0.82 | OXER1 (0.44) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL7412570 | 0.81 | LMNA (0.48) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL7407743 | 0.76 | NR4A2 (0.44) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL6686573 | 0.72 | AHR (0.51) | LMNAALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL14555859 | 0.72 | OXER1 (0.53) | LMNAALDH1A1KDM4EHPGDNR4A2 | |
| SCHEMBL7423432 | 0.72 | KMT2A (0.62) | ALDH1A1L3MBTL1KDM4EHPGDHTT | |
| SCHEMBL7474876 | 0.71 | NR4A2 (0.61) | LMNAALDH1A1L3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |