Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296463 | 0.84 | CTSL (0.47) | CTSBCTSSCTSLDDB1CRBN | |
| SCHEMBL7360632 | 0.83 | CTSL (0.49) | CTSBCTSSCTSLDDB1CRBN | |
| SCHEMBL6166888 | 0.79 | DDB1 (0.48) | DDB1CRBNALDH1A1 | |
| SCHEMBL15114553 | 0.79 | ALDH1A1 (0.49) | DDB1CRBNALDH1A1 | |
| SCHEMBL7411019 | 0.79 | CTSL (0.46) | CTSBCTSSCTSLDDB1CRBN | |
| SCHEMBL7916887 | 0.78 | CTSB (0.47) | CTSBCTSSCTSLALDH1A1 | |
| SCHEMBL12661032 | 0.78 | CTSL (0.54) | CTSBCTSSCTSLDDB1CRBN | |
| SCHEMBL13177736 | 0.78 | CTSL (0.54) | CTSBCTSSCTSLDDB1CRBN | |
| SCHEMBL15461470 | 0.77 | CTSB (0.50) | CTSBCTSSCTSLDDB1CRBN | |
| SCHEMBL27175299 | 0.76 | CTSL (0.46) | CTSBCTSSCTSLALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007052301-A2 | PROCESS FOR THE PREPARATION OF IRBESARTAN | ALEMBIC LIMITED (IN) | 2007-05-10 | — | — | WO | disclosed |