Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411184 | 1.00 | CTSK (0.47) | CTSKCASP1MMECTSLCTSB | |
| SCHEMBL14598492 | 0.82 | CTSK (0.52) | CTSK | |
| SCHEMBL7406391 | 0.81 | CTSB (0.44) | CTSKMMECTSLCTSBCTSS | |
| SCHEMBL7412037 | 0.75 | REN (0.38) | CTSKCASP1 | |
| SCHEMBL14355711 | 0.73 | CTSK (0.50) | CTSK | |
| SCHEMBL7404509 | 0.70 | MME (0.40) | CTSKMMECTSLCTSBCTSS | |
| SCHEMBL7409805 | 0.70 | CTSB (0.46) | CTSKMMECTSLCTSBCTSS | |
| SCHEMBL5489915 | 0.69 | CTSK (0.39) | CTSKCTSLCTSBCTSS | |
| SCHEMBL14598495 | 0.67 | CASP1 (0.43) | CTSKCASP1 | |
| SCHEMBL7412892 | 0.65 | MME (0.39) | CTSKMMECTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076968-A1 | MALONATES AS INHIBITORS OF THE ICE/CED-6 FAMILY OF CYSTEINE PROTEASES | NOVARTIS AG (CH) | 2002-10-03 | — | — | WO | disclosed |