SCHEMBL74112

SCHEMBL74112

c1ccc(-c2c(-c3ccc(N(c4ccccc4)c4ccc(-c5ccc(N(c6ccccc6)c6ccc(-c7oc8ccccc8c7-c7ccccc7)cc6)cc5)cc4)cc3)oc3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 3/20 0.47
▸ PLA2G2A P14555 1/20 0.47
▸ PLA2G4A P47712 1/20 0.47
▸ PTGS1 P23219 1/20 0.47
▸ CHRM2 P08172 1/20 0.44
▸ CHRM4 P08173 1/20 0.44
▸ CHRM5 P08912 1/20 0.44
▸ CHRM1 P11229 1/20 0.44
▸ CHRM3 P20309 1/20 0.44
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ CA1 P00915 2/20 0.43
▸ CA2 P00918 2/20 0.43
▸ CYP3A4 P08684 2/20 0.43
▸ ALOX15 P16050 2/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ DDR2 Q16832 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74456 1.00 PTGS2 (0.47) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL18540439 0.98 PTGS2 (0.48) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26828034 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26824374 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26822378 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26826888 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26822351 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26822385 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26827159 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2
SCHEMBL26824403 0.91 L3MBTL1 (0.45) PTGS2PLA2G2APLA2G4APTGS1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 — — US disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 — — US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 — — US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 — — US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 — — US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 — — US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 — — US disclosed
US-9444053-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-13 — — US disclosed
US-9444053-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-13 — — US disclosed
US-9306173-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-04-05 — — US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 — — US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 — — US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 — — US disclosed
EP-2109898-B1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2011-08-17 — — EP disclosed
US-7504163-B2 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY (US) 2009-03-17 — — US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 — — US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 — — US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 — — US disclosed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 — — US disclosed
US-20060008672-A1 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY 2006-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 PTGS2 4823/4885PLA2G2A 3305/4885PLA2G4A 3622/4885
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same ALK, ALKBH3, ACVRL1 PTGS2 4716/4885PLA2G2A 4115/4885PLA2G4A 3663/4885
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 PTGS2 4823/4885PLA2G2A 3305/4885PLA2G4A 3622/4885
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 PTGS2 4823/4885PLA2G2A 3305/4885PLA2G4A 3622/4885
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 PTGS2 4823/4885PLA2G2A 3305/4885PLA2G4A 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback