Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407188 | 1.00 | NPC1 (0.41) | NPC1 | |
| SCHEMBL7410695 | 0.80 | L3MBTL1 (0.45) | — | |
| SCHEMBL7406898 | 0.80 | L3MBTL1 (0.45) | — | |
| SCHEMBL7412072 | 0.78 | L3MBTL1 (0.41) | — | |
| SCHEMBL7408913 | 0.78 | — | — | |
| SCHEMBL7411267 | 0.78 | L3MBTL1 (0.48) | — | |
| SCHEMBL7408082 | 0.78 | — | — | |
| SCHEMBL7410495 | 0.77 | L3MBTL1 (0.44) | NPC1 | |
| SCHEMBL7413206 | 0.77 | UCHL1 (0.40) | — | |
| SCHEMBL7412111 | 0.77 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973775-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043975-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |