Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408785 | 0.88 | PARP1 (0.57) | PARP1PARP2 | |
| SCHEMBL7416833 | 0.81 | PARP1 (0.57) | PARP1PARP2 | |
| SCHEMBL7415820 | 0.80 | PARP1 (0.56) | PARP1PARP2 | |
| SCHEMBL7043271 | 0.79 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL6869625 | 0.79 | PARP1 (0.69) | PARP1PARP2 | |
| SCHEMBL7415905 | 0.75 | PARP1 (0.50) | PARP1PARP2 | |
| SCHEMBL7045124 | 0.73 | PARP1 (0.53) | PARP1PARP2 | |
| SCHEMBL7417446 | 0.73 | HTR3A (0.40) | PARP1 | |
| SCHEMBL7040728 | 0.73 | PARP1 (0.51) | PARP1PARP2 | |
| SCHEMBL5620854 | 0.72 | PARP1 (0.64) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133477-A1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032579-A1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |