Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412016 | 0.92 | HTR1F (0.40) | HTR1FHTR6MEN1KMT2ACHRM3 | |
| SCHEMBL7411529 | 0.90 | HTR1F (0.43) | HTR1FRXFP1HTR6ALDH1A1LMNA | |
| SCHEMBL7409286 | 0.80 | HTR1F (0.37) | HTR1FHTR6ALDH1A1KMT2ACHRM3 | |
| SCHEMBL7410521 | 0.79 | HTR1F (0.41) | HTR1FHTR6ALDH1A1LMNACHRM3 | |
| SCHEMBL7407854 | 0.79 | CHRM3 (0.44) | HTR1FCHRM3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7407442 | 0.78 | HTR1F (0.41) | HTR1FHTR6ALDH1A1LMNACHRM3 | |
| SCHEMBL7408142 | 0.77 | HTR1F (0.47) | HTR1FALDH1A1LMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7407346 | 0.77 | ALDH1A1 (0.44) | HTR1FALDH1A1LMNAKDM4E | |
| SCHEMBL7417232 | 0.77 | BRD4 (0.41) | HTR1FALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL7412099 | 0.76 | CHRM3 (0.40) | HTR1FCHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |