Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412016 | 0.82 | HTR1F (0.40) | HTR1FCHRM3KMT2AHTR6 | |
| SCHEMBL7407854 | 0.78 | CHRM3 (0.44) | HTR1FCHRM3 | |
| SCHEMBL7411529 | 0.78 | HTR1F (0.43) | HTR1FALDH1A1HTR6 | |
| Hydrochloric Acid SCHEMBL7407346 | 0.75 | ALDH1A1 (0.44) | HTR1FALDH1A1 | |
| SCHEMBL7417232 | 0.72 | BRD4 (0.41) | HTR1FKMT2AALDH1A1 | |
| SCHEMBL7409296 | 0.71 | HTR6 (0.41) | HTR1FHTR6 | |
| Water SCHEMBL7414567 | 0.71 | GFER (0.57) | HTR1FCHRM3KMT2AHTR6 | |
| Hydrochloric Acid SCHEMBL7408008 | 0.71 | CHRM3 (0.55) | HTR1FCHRM3 | |
| SCHEMBL7417151 | 0.70 | HTR1F (0.47) | HTR1FCHRM3HTR6 | |
| SCHEMBL7409054 | 0.69 | LMNA (0.39) | HTR1FCHRM3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |